Mighty Mitochondria
Methylation
Methylation is the master switch that uses methyl groups to activate the biochemical process in all of our major body systems. Methylation is an important component for detox in our kids, as well as a necessary step in the production of neurotransmitters. And, importantly, methylation is even a part of the defense against the activation of retrovirus. However, stressors, of any kind, chew up these methyl groups.
“Retroviruses are a diverse family of animal viruses that contain RNA as their genetic material but produce a double-stranded DNA copy of their genome upon infection. This dual genetic system allows transmission of virus from cell to cell as packaged RNA while leaving a DNA copy in the chromosomes of each infected cell, where it can be transmitted from one cell generation to the next.”¹
And if methyl groups are not available, retroviruses will be harder to silence. For healthy methylation, we need optimal cellular mitochondria. Mitochondria have the unique function of being the only cellular organelle to contain an independent genome (mtDNA). This mitochonmitochondrial DNA can be found in different numbers and “versions” depending on the cell type, the tissue type, and the epigenetic (genetic) instructions.² So when it comes to disease and dysfunction, we like to say, “Genetics load the gun, but environment pulls the trigger.”
Mitochondria are the powerhouse of the cell, essentially the batteries of the body. Mitochondria Dysfunction is present in many modern health issues we are seeing in kids. Mitochondria also control the cell danger response.
The cell danger response is the body’s reaction to stress, or dorsal vagal activation.
“The dorsal (back) side of the vagus nerve responds to cues of danger. It pulls us away from connection, out of awareness, and into a state of self-protection. In moments when we might experience a cue of extreme danger, we can shut down and feel frozen, an indication that our dorsal vagal nerve has taken over.”³
But when that mitochondrial control dysfunctions, the extended dorsal vagal response is no longer “fight or flight,” but instead a parasympathetic response that is different than “rest and digest.” Some parents will talk about their child seeming indifferent, lacking emotion, and/or lacking energy. It is not uncommon for systems in dysfunction to get stuck in a cell danger response.
But please note:
While healthy mitochondria function is a crucial part of our overall health, for some kids, specifically kids with brain inflammation, turning on mitochondria too soon can be problematic. Focus on lowering overall inflammation, first.
Disclaimer: The following information is not intended to be, nor should they be construed as a claim or representation of medical diagnosis or treatment. It is for informational purposes only.